/* node_modules/@angular/cdk/overlay-prebuilt.css */
.cdk-overlay-container,
.cdk-global-overlay-wrapper {
  pointer-events: none;
  top: 0;
  left: 0;
  height: 100%;
  width: 100%;
}
.cdk-overlay-container {
  position: fixed;
  z-index: 1000;
}
.cdk-overlay-container:empty {
  display: none;
}
.cdk-global-overlay-wrapper {
  display: flex;
  position: absolute;
  z-index: 1000;
}
.cdk-overlay-pane {
  position: absolute;
  pointer-events: auto;
  box-sizing: border-box;
  display: flex;
  max-width: 100%;
  max-height: 100%;
  z-index: 1000;
}
.cdk-overlay-backdrop {
  position: absolute;
  top: 0;
  bottom: 0;
  left: 0;
  right: 0;
  pointer-events: auto;
  -webkit-tap-highlight-color: transparent;
  opacity: 0;
  touch-action: manipulation;
  z-index: 1000;
  transition: opacity 400ms cubic-bezier(0.25, 0.8, 0.25, 1);
}
@media (prefers-reduced-motion) {
  .cdk-overlay-backdrop {
    transition-duration: 1ms;
  }
}
.cdk-overlay-backdrop-showing {
  opacity: 1;
}
@media (forced-colors: active) {
  .cdk-overlay-backdrop-showing {
    opacity: 0.6;
  }
}
.cdk-overlay-dark-backdrop {
  background: rgba(0, 0, 0, 0.32);
}
.cdk-overlay-transparent-backdrop {
  transition: visibility 1ms linear, opacity 1ms linear;
  visibility: hidden;
  opacity: 1;
}
.cdk-overlay-transparent-backdrop.cdk-overlay-backdrop-showing,
.cdk-high-contrast-active .cdk-overlay-transparent-backdrop {
  opacity: 0;
  visibility: visible;
}
.cdk-overlay-backdrop-noop-animation {
  transition: none;
}
.cdk-overlay-connected-position-bounding-box {
  position: absolute;
  display: flex;
  flex-direction: column;
  min-width: 1px;
  min-height: 1px;
  z-index: 1000;
}
.cdk-global-scrollblock {
  position: fixed;
  width: 100%;
  overflow-y: scroll;
}
.cdk-overlay-popover {
  background: none;
  border: none;
  padding: 0;
  outline: 0;
  overflow: visible;
  position: fixed;
  pointer-events: none;
  white-space: normal;
  color: inherit;
  text-decoration: none;
  width: 100%;
  height: 100%;
  inset: auto;
  top: 0;
  left: 0;
}
.cdk-overlay-popover::backdrop {
  display: none;
}
.cdk-overlay-popover .cdk-overlay-backdrop {
  position: fixed;
  z-index: auto;
}

/* src/styles.css */
.msp-plugin .msp-layout-expanded {
  z-index: 100 !important;
}
.new-row {
  max-width: 1440px;
  padding: 2px 34px;
}
.vf-footer::after {
  width: unset !important;
}
html {
  scroll-behavior: smooth;
}
#masthead-black-bar,
#global-footer {
  background: #54585a;
}
#global-footer .readmore {
  display: none;
}
.pae-x-axis {
  margin: 330px 0 0 0;
  position: absolute;
}
.pae-y-axis {
  margin: 0 0 0 0;
  position: absolute;
}
.pae-axis-box .tick {
  font-weight: 500;
  font-size: 14px;
  color: #000000;
}
.pae-axis-box .domain,
.pae-axis-box line {
}
a:not(.vf-button) {
  box-shadow: none;
}
.pae-axes {
  width: 430px;
  height: 430px;
  margin-left: none;
}
.pae-x-lable {
  --pae-x-label-shift-x: -76px;
  --pae-x-label-shift-y: 146px;
  -webkit-transform: translate(var(--pae-x-label-shift-x), var(--pae-x-label-shift-y)) rotate(-90deg);
  transform: translate(var(--pae-x-label-shift-x), var(--pae-x-label-shift-y)) rotate(-90deg);
  transform-box: view-box;
}
@media screen and (max-width: 39.9375em) {
  .pae-axis-box .tick {
    font-weight: 500;
    font-size: 10px;
  }
  .pae-x-axis {
    margin: 265px 0 0 41px;
  }
  .pae-y-axis {
    margin: 12px 0 0 12px;
  }
  .pae-axes {
    width: 389px;
    height: 380px;
    margin-left: -47px;
    margin-top: 5px;
  }
  .pae-x-lable {
    --pae-x-label-shift-x: -46px;
    --pae-x-label-shift-y: 125px;
    -webkit-transform: translate(var(--pae-x-label-shift-x), var(--pae-x-label-shift-y)) rotate(-90deg);
    transform: translate(var(--pae-x-label-shift-x), var(--pae-x-label-shift-y)) rotate(-90deg);
    transform-box: view-box;
  }
  @supports ((-webkit-touch-callout: none) or (font: -apple-system-body)) {
    .pae-x-lable {
      --pae-x-label-shift-x: -94px;
      --pae-x-label-shift-y: 77px;
      -webkit-transform: translate(var(--pae-x-label-shift-x), var(--pae-x-label-shift-y)) rotate(-90deg);
      transform: translate(var(--pae-x-label-shift-x), var(--pae-x-label-shift-y)) rotate(-90deg);
      transform-origin: center;
    }
  }
}
@font-face {
  font-family: "DM Sans";
  font-style: normal;
  font-weight: 400;
  font-display: swap;
  src: url(https://fonts.gstatic.com/s/dmsans/v6/rP2Hp2ywxg089UriCZOIHQ.woff2) format("woff2");
}
@font-face {
  font-family: "IBM Plex Sans";
  font-style: normal;
  font-weight: 400;
  font-display: swap;
  src:
    local("IBM Plex Sans"),
    local("IBMPlexSans"),
    url(https://assets.emblstatic.net/vf/v2.5.0-beta.2/assets/vf-font-plex-sans/assets/IBM-Plex-Sans/fonts/complete/woff/IBMPlexSans-Regular.woff) format("woff");
}
@font-face {
  font-family: "IBM Plex Sans";
  font-style: normal;
  font-weight: 700;
  font-display: swap;
  src:
    local("IBM Plex Sans Bold"),
    local("IBMPlexSans-Bold"),
    url(https://assets.emblstatic.net/vf/v2.5.0-beta.2/assets/vf-font-plex-sans/assets/IBM-Plex-Sans/fonts/complete/woff/IBMPlexSans-Bold.woff) format("woff");
}
@font-face {
  font-family: "IBM Plex Sans";
  font-style: normal;
  font-weight: 500;
  font-display: swap;
  src:
    local("IBM Plex Sans Medium"),
    local("IBMPlexSans-Medium"),
    url(https://assets.emblstatic.net/vf/v2.5.0-beta.2/assets/vf-font-plex-sans/assets/IBM-Plex-Sans/fonts/complete/woff/IBMPlexSans-Medium.woff) format("woff");
}
@font-face {
  font-family: "IBM Plex Mono";
  font-style: normal;
  font-weight: 400;
  font-display: swap;
  src:
    local("IBM Plex Mono"),
    local("IBMPlexMono"),
    url(https://assets.emblstatic.net/vf/v2.5.0-beta.2/assets/vf-font-plex-mono/assets/IBM-Plex-Mono/fonts/complete/woff/IBMPlexMono-Regular.woff) format("woff");
}
@font-face {
  font-family: "EBI-Common";
  font-weight: normal;
  font-style: normal;
  font-display: swap;
  src: url(https://ebi.emblstatic.net/web_guidelines/EBI-Icon-fonts/v1.3/EBI-Common/fonts/EBI-Common.woff2) format("woff2"), url(https://ebi.emblstatic.net/web_guidelines/EBI-Icon-fonts/v1.3/EBI-Common/fonts/EBI-Common.woff) format("woff");
}
@font-face {
  font-family: "EBI-Conceptual";
  font-weight: normal;
  font-style: normal;
  font-display: swap;
  src: url(https://ebi.emblstatic.net/web_guidelines/EBI-Icon-fonts/v1.3/EBI-Conceptual/fonts/EBI-Conceptual.woff2) format("woff2"), url(https://ebi.emblstatic.net/web_guidelines/EBI-Icon-fonts/v1.3/EBI-Conceptual/fonts/EBI-Conceptual.woff) format("woff");
}
@font-face {
  font-family: "EBI-Functional";
  font-weight: normal;
  font-style: normal;
  font-display: swap;
  src: url(https://ebi.emblstatic.net/web_guidelines/EBI-Icon-fonts/v1.3/EBI-Functional/fonts/EBI-Functional.woff2) format("woff2"), url(https://ebi.emblstatic.net/web_guidelines/EBI-Icon-fonts/v1.3/EBI-Functional/fonts/EBI-Functional.woff) format("woff");
}
@font-face {
  font-family: "EBI-Generic";
  font-weight: normal;
  font-style: normal;
  font-display: swap;
  src: url(https://ebi.emblstatic.net/web_guidelines/EBI-Icon-fonts/v1.3/EBI-Generic/fonts/EBI-Generic.woff2) format("woff2"), url(https://ebi.emblstatic.net/web_guidelines/EBI-Icon-fonts/v1.3/EBI-Generic/fonts/EBI-Generic.woff) format("woff");
}
@font-face {
  font-family: "EBI-Species";
  font-weight: normal;
  font-style: normal;
  font-display: swap;
  src: url(https://ebi.emblstatic.net/web_guidelines/EBI-Icon-fonts/v1.3/EBI-Species/fonts/EBI-Species.woff2) format("woff2"), url(https://ebi.emblstatic.net/web_guidelines/EBI-Icon-fonts/v1.3/EBI-Species/fonts/EBI-Species.woff) format("woff");
}
.af-footer {
  background-color: #f3f3f3;
}
.af-footer > div > div {
  height: 40px;
  line-height: 40px;
  margin-top: 24px;
  margin-bottom: 24px;
  padding-left: 0px !important;
}
.af-footer-logos {
  text-align: right;
}
.af-footer-logos > a {
  text-decoration: none;
  border-bottom: none;
  display: inline-block;
}
.af-footer-logos > a:last-child {
  margin-left: 50px;
}
.af-footer-logos img {
  height: 40px;
  width: auto;
}
.af-footer-text {
  font-weight: 500;
  font-size: 19px;
}
.faq-content a {
  border-bottom: none;
  color: #3b6fb6 !important;
}
.faq-content a:hover {
  text-decoration-line: underline;
  border-bottom: none;
  color: #1d477f !important;
}
.faq-content li {
  margin-bottom: 15px;
}
.faq-circle {
  list-style-type: circle !important;
}
.faq-circle-bullet {
  margin-bottom: 0px !important;
}
.monospace {
  font-family: monospace;
}
.for-big {
  display: block;
}
.for-mobile {
  display: none;
}
@media screen and (max-width: 39.9375em) {
  .for-big {
    display: none;
  }
  .for-mobile {
    display: block;
  }
  .af-footer > div > div {
    height: 23px;
    line-height: 23px;
    margin-top: 15px;
    margin-bottom: 15px;
  }
  .af-footer-text {
    padding-right: 0;
    font-weight: 400;
    font-size: 14px;
  }
  .af-footer-logos {
    padding-left: 0;
  }
  .af-footer-logos img {
    height: 25px;
    width: auto;
  }
  .af-footer-logos > a:last-child {
    margin-left: 12px;
  }
}
a.ext {
  margin-left: 10px;
}
a.ext:after {
  content: " x";
  font-family: "EBI-Generic";
  font-size: 0.65rem;
  position: relative;
  top: -1px;
  margin-left: 4px;
}
.msp-plugin .msp-viewport {
  background: #fff !important;
}
.msp-plugin .msp-layout-standard {
  border: none !important;
}
.structureTable tbody tr:nth-child(even) {
  border-bottom: 0;
  background-color: #ffffff !important;
}
.structureTable tbody tr:nth-child(1) {
  border-bottom: 0;
  background-color: #ffffff !important;
}
.msp-plugin .msp-layout-standard-outside .msp-layout-top {
  border-bottom: none !important;
}
.mmseqTable tbody tr:nth-child(even) {
  background-color: #f3f3f3 !important;
}
.struct-table .mat-mdc-tab-labels {
  border-bottom: 1px solid #d0d0ce !important;
}
.struct-table .mdc-tab-indicator__content--underline {
  display: none;
}
.struct-table .mdc-tab--active.mdc-tab-indicator--active {
  border-bottom: 3px solid #3b6fb6 !important;
}
.struct-table .mdc-tab.mat-mdc-tab {
  height: 58px;
}
.struct-table .mdc-tab.mat-mdc-tab .mdc-tab__text-label {
  font-size: 19px !important;
  font-style: normal !important;
  font-weight: 400 !important;
  line-height: 28.5px !important;
  color: #1a1c1a !important;
}
.struct-table .mdc-tab.mat-mdc-tab.mdc-tab--active .mdc-tab__text-label {
  font-size: 19px !important;
  font-style: normal !important;
  font-weight: 500 !important;
  line-height: 28.5px !important;
  color: #3b6fb6 !important;
}
.struct-table .mdc-tab.mat-mdc-tab.mdc-tab--active {
  background: var(--Brand-50, #fff);
  border-bottom: 3px solid #3b6fb6 !important;
}
.struct-table .mat-mdc-tab-body {
  overflow-x: hidden;
  overflow-y: hidden;
}
.struct-table .mat-mdc-tab-body-content {
  overflow: hidden !important;
}
.struct-table .mat-mdc-tab-group.mat-mdc-tab-group-stretch-tabs > .mat-mdc-tab-header .mat-mdc-tab:hover {
  border-radius: var(--similar-clusters-table-description-max, 0px);
  border-bottom: 3px solid var(--neutral-600, #707372);
  background: #fff;
}
.struct-table .mat-mdc-tab.mdc-tab__content:hover {
  font-weight: bold;
}
.mat-mdc-table .mat-mdc-header-cell {
  background: inherit;
  font-weight: 600 !important;
  text-align: left;
  font-size: 16px !important;
  padding: 0 3px 0 8px !important;
  overflow: visible;
}
.struct-table .mat-mdc-tab-label-container {
  border-style: none !important;
}
.struct-table .mdc-tab.mat-mdc-tab {
  border: unset !important;
  background: white !important;
}
.struct-table .mdc-tab.mat-mdc-tab::after {
  content: "";
  position: absolute;
  right: 0;
  top: 50%;
  width: 0px !important;
  height: 0px !important;
  transform: none !important;
}
.struct-table .mdc-tab .mat-mdc-tab .mat-focus-indicator {
  background: #ffffff !important;
}
.training-wrapper .mat-mdc-tab-group .mdc-tab__text-label {
  font-size: 30px !important;
}
.mat-mdc-icon-button[disabled],
.mat-mdc-icon-button.mat-mdc-button-disabled {
  opacity: 0.38 !important;
  color: #373a36 !important;
  height: auto !important;
  padding: 0 !important;
}
.mat-mdc-button .mdc-button__label {
  display: flex;
}
.mat-mdc-icon-button:disabled {
  opacity: 0.38 !important;
}
.mat-mdc-icon-button {
  color: #373a36 !important;
  height: auto !important;
  padding: 0 !important;
}
.mat-tab-label:hover:not(.mat-tab-disabled) {
  background-color: rgb(206, 206, 206);
}
.mdc-notched-outline__trailing {
  border-top: none !important;
}
.mdc-text-field--outlined .mdc-notched-outline .mdc-notched-outline__leading {
  border-top-left-radius: none !important;
  border-top-right-radius: none !important;
  border-bottom-right-radius: none !important;
  border-bottom-left-radius: none !important;
}
.mdc-notched-outline__leading {
  border-left: none !important;
  border-right: none !important;
}
.mdc-notched-outline__leading,
.mdc-notched-outline__notch,
.mdc-notched-outline__trailing {
  border-top: none !important;
  border-bottom: none !important;
  border-right: none !important;
}
.mat-mdc-paginator .mat-mdc-select {
  border-bottom: 1px solid #000000;
}
.mat-mdc-paginator .mat-mdc-paginator-page-size-label {
  font-family: "IBM Plex Sans", sans-serif !important;
  color: #373a36 !important;
  font-size: 16px !important;
  font-style: normal !important;
  line-height: 16.5px !important;
}
#mat-paginator-page-size-label-2,
.mat-mdc-paginator-range-label,
.mat-mdc-select-min-line {
  font-family: "IBM Plex Sans", sans-serif !important;
  color: #373a36 !important;
  font-size: 16px !important;
  font-style: normal !important;
  line-height: 16.5px !important;
}
.mat-mdc-option.mdc-list-item {
  min-height: 35px;
}
.mat-mdc-paginator .mat-mdc-select-arrow svg {
  fill: #373a36 !important;
}
.mat-mdc-option.mdc-list-item--selected:not(.mdc-list-item--disabled):not(.mat-mdc-option-multiple) {
  background-color: #f2f2f2;
  min-height: 35px;
}
.mat-mdc-option:hover {
  background-color: #f2f2f2;
}
.mdc-menu-surface.mat-mdc-select-panel {
  width: 74% !important;
  margin-left: 10px !important;
  border: 1px solid #d0d0ce !important;
  padding: 0px !important;
  background: white;
}
.mmseqTable .mobile-view {
  display: none;
  margin-right: 20px;
}
.mmseqTable .badgeTitleSvg {
  padding-right: 5px;
}
.mmseqTable a {
  color: #3b6fb6 !important;
  text-decoration: none !important;
  border-bottom: none !important;
  display: block;
  width: 162px;
}
.mmseqTable a:hover {
  color: #3b6fb6 !important;
  text-decoration: underline !important;
}
.mdc-data-table__cell {
  font-size: 16px !important;
  font-style: normal !important;
  font-weight: 400 !important;
  align-items: center !important;
}
.mmseqTable .mdc-data-table__row:last-child .mdc-data-table__cell {
  border-bottom: 1px solid #d0d0ce;
}
.mmseqTable .mdc-data-table__cell {
  vertical-align: top;
  padding-top: 12px;
  padding-bottom: 12px;
  overflow: visible;
  padding-left: 8px;
  padding-right: 8px;
}
.mat-mdc-paginator-range-label {
  margin: 0;
}
.mat-mdc-option .mdc-list-item__primary-text {
  font-size: 14px !important;
}
.mat-sort-header-content {
  text-align: left !important;
}
.mdc-data-table__cell,
.mdc-data-table__header-cell {
  padding: 0 8px 0 8px;
}
.mat-mdc-header-row .mdc-data-table__header-row th {
  padding: 0 8px 0 8px;
}
.mat-sort-header-container {
  align-items: baseline !important;
}
.mat-button-toggle-appearance-standard {
  background-color: #eceff3 !important;
}
.mat-button-toggle-group {
  background-color: #b9d4f1;
  max-width: 624px;
  overflow: visible !important;
}
.mat-button-toggle-group > .mat-button-toggle:not(:last-child) {
  border-right: 1px solid #3b6fb6;
}
.mat-button-toggle {
  background-color: #eceff3;
  width: 500px;
}
.mat-button-toggle:hover {
  color: black;
  background-color: #d1e3f6;
}
.mat-button-toggle-checked {
  background-color: #b9d4f1;
}
.mat-button-toggle-appearance-standard.mat-button-toggle-checked {
  background-color: #b9d4f1 !important;
  width: 500px;
}
.mat-button-toggle-appearance-standard .mat-button-toggle-label-content {
  padding: 0 12px;
  line-height: 36px !important;
}
.mat-button-toggle-group-appearance-standard {
  border: 1px solid #3b6fb6 !important;
  border-radius: unset !important;
}
@media screen and (width: 768px) or (width: 820px) {
  .mat-mdc-header-row {
    display: none;
  }
  .mdc-data-table__row {
    height: 301px !important;
    border-bottom: 1px solid var(--neutral-300, #d0d0ce);
    background: #fff !important;
    box-shadow: 1px 1px 4px 0px rgba(0, 0, 0, 0.25);
    padding: 8px 4px;
    flex-direction: column;
  }
  .mdc-data-table__cell {
    display: flex;
    font-size: 14px;
    font-style: normal;
    font-weight: 500;
    align-items: center;
    vertical-align: top;
    padding-top: 12px;
    padding-bottom: 12px;
  }
  .mat-column-afdbAccessions {
    border-bottom: 1px solid #d0d0ce !important;
    padding: 0 8px 0 8px;
  }
  .mat-column-uniprotDescriptions {
    border-bottom: 1px solid #d0d0ce !important;
    padding: 0 8px 0 8px;
  }
  .mat-mdc-cell {
    font-size: 14px;
    font-weight: 400;
    padding-top: 8px;
    align-items: center;
  }
  .mat-mdc-row {
    width: 100%;
    display: grid;
    height: 100px;
    border: 1px solid #d0d0ce;
    margin-bottom: 8px;
  }
  .mmseqTable .mobile-view {
    display: block;
  }
  .mmseqTable .nonMobile {
    display: none;
  }
  .mmseqTable .mobile-view-title {
    min-width: 30%;
    font-size: 14px;
    font-style: normal;
    font-weight: 500;
    padding-top: 5px;
  }
  .mat-column-averagePlddt {
    border-bottom: none !important;
  }
  .mmseqTable a {
    width: 149px;
    margin-right: 10px;
  }
  .pae-axis-box .tick {
    font-weight: 500;
    font-size: 10px;
  }
  .pae-x-axis {
    margin: 265px 0 0 41px;
  }
  .pae-y-axis {
    margin: 12px 0 0 12px;
  }
  .pae-axes {
    width: 389px;
    height: 380px;
    margin-left: -47px;
    margin-top: 5px;
  }
  .pae-x-lable {
    --pae-x-label-shift-x: -46px;
    --pae-x-label-shift-y: 125px;
    -webkit-transform: translate(var(--pae-x-label-shift-x), var(--pae-x-label-shift-y)) rotate(-90deg);
    transform: translate(var(--pae-x-label-shift-x), var(--pae-x-label-shift-y)) rotate(-90deg);
    transform-box: view-box;
  }
  @supports ((-webkit-touch-callout: none) or (font: -apple-system-body)) {
    .pae-x-lable {
      --pae-x-label-shift-x: -94px;
      --pae-x-label-shift-y: 77px;
      -webkit-transform: translate(var(--pae-x-label-shift-x), var(--pae-x-label-shift-y)) rotate(-90deg);
      transform: translate(var(--pae-x-label-shift-x), var(--pae-x-label-shift-y)) rotate(-90deg);
      transform-origin: center;
    }
  }
}
@media (min-width: 1440px) and (min-height: 1080px) {
  .mmseqTable .mobile-view {
    display: none;
  }
}
@media (min-width: 1920px) and (min-height: 1080px) {
  .mmseqTable .mobile-view {
    display: none;
  }
}
@media (min-width: 1024px) and (min-height: 1366px) {
  .mat-mdc-header-row {
    display: none;
  }
  .mdc-data-table__row {
    height: 270px !important;
    border-bottom: 1px solid #d0d0ce;
    background: #fff;
    box-shadow: 1px 1px 4px 0px rgba(0, 0, 0, 0.25);
    padding: 8px 4px;
    flex-direction: column;
  }
  .mdc-data-table__cell {
    display: flex;
    font-size: 14px;
    font-style: normal;
    font-weight: 500;
    align-items: center;
  }
  .mat-mdc-cell {
    font-size: 14px;
    font-weight: 400;
    padding-top: 8px;
    align-items: flex-end;
    padding-bottom: 8px;
    align-items: center;
  }
  .mat-mdc-row {
    width: 100%;
    display: grid;
    height: 100px;
    border: 1px solid #d0d0ce;
    margin-bottom: 8px;
  }
  .mmseqTable .mobile-view {
    display: block;
  }
  .mmseqTable .mobile-view-title {
    min-width: 18%;
    font-size: 14px;
    font-style: normal;
    font-weight: 500;
    padding-top: 5px;
  }
  .mmseqTable .nonMobile {
    display: none;
  }
  .mat-column-averagePlddt {
    border-bottom: none !important;
  }
  .mmseqTable a {
    width: 139px;
    margin-right: 10px;
  }
}
@media (width: 640px) and (height: 1080px) {
  .mmseqTable .mobile-view {
    display: none;
  }
}
@media (width: 1080px) and (height: 1080px) {
  .mmseqTable .mobile-view {
    display: none;
  }
}
@media (width: 990px) and (height: 1080px) {
  .mmseqTable .mobile-view {
    display: none;
  }
}
@media screen and (max-width: 64.625em) {
  .new-row {
    max-width: 1440px;
    padding: 2px 24px;
  }
}
@media screen and (max-width: 39.9375em) {
  .new-row {
    max-width: 1440px;
    padding: 2px 12px;
  }
  .mat-mdc-header-row {
    display: none;
  }
  .mdc-data-table__row {
    height: 344px !important;
    border-bottom: 1px solid #d0d0ce;
    background: #fff;
    box-shadow: 1px 1px 4px 0px rgba(0, 0, 0, 0.25);
    padding: 8px 4px;
    flex-direction: column;
  }
  .mdc-data-table__cell {
    display: flex;
    font-size: 14px;
    font-style: normal;
    font-weight: 500;
    align-items: center;
  }
  .mat-mdc-cell {
    font-size: 14px;
    font-weight: 400;
    padding-top: 8px;
    align-items: flex-end;
    padding-bottom: 8px;
    align-items: center;
  }
  .mat-mdc-row {
    width: 100%;
    display: grid;
    height: 100px;
    border: 1px solid #d0d0ce;
    margin-bottom: 8px;
  }
  .mmseqTable .mobile-view {
    display: block;
  }
  .mmseqTable .mobile-view-title {
    min-width: 30%;
    font-size: 14px;
    font-style: normal;
    font-weight: 600;
  }
  .mmseqTable .nonMobile {
    display: none;
  }
  .mat-column-averagePlddt {
    border-bottom: none !important;
  }
  .mmseqTable a {
    width: 139px;
    margin-right: 10px;
  }
  .mat-button-toggle-appearance-standard .mat-button-toggle-label-content {
    padding: 0 12px;
    line-height: 36px !important;
    font-size: 14px !important;
  }
}
.groupLevel {
  background-color: darkgray;
  font-size: 25px;
  width: 150px;
}
.buttonToggleLevel {
  color: beige;
  width: 150px;
}
.pvTracks_0 {
  display: none;
}
.pvVariantPlotSection svg {
  box-sizing: unset !important;
}
#plotAreaClip {
  display: none !important;
}
.category-label {
  background-color: #b9d4f1 !important;
}
.track-label {
  background-color: #eceff3 !important;
}
.protvistaCol1 protvista-filter > div > div > div:nth-child(4) protvista-checkbox {
  display: none !important;
}
.protvistaCol1 protvista-filter > div > div > h5:nth-child(3) {
  display: none !important;
}
.protvistaCol1 protvista-filter > div > div > div:nth-child(2) protvista-checkbox {
  display: none !important;
}
.protvistaCol1 protvista-filter > div > div > h5:nth-child(1) {
  display: none !important;
}
.pvHideOptionsTable tr:first-child {
  display: none !important;
}
.uncertainBox .mat-mdc-slider {
  width: 170px !important;
}
.uncertainBox .mdc-slider .mdc-slider__thumb-knob {
  background-color: #a9abaa !important;
  border-radius: unset !important;
  width: 12px !important;
  height: 20px !important;
  padding: 2px 4px !important;
  border-style: none !important;
  border-width: calc(var(--mat-slider-handle-height, 20px) / 2) calc(var(--mat-slider-handle-width, 20px) / 2);
}
.uncertainBox .mat-mdc-slider .mdc-slider__track {
  height: 4px !important;
}
.uncertainBox .mdc-slider__thumb:last-child > .mdc-slider__thumb-knob {
  background-color: #a9abaa !important;
}
.uncertainBox .mat-mdc-slider .mdc-slider__track--active_fill {
  border-color: #a9abaa;
  background-color: #a9abaa;
}
.uncertainBox .mat-mdc-slider .mdc-slider__track .mdc-slider__track--inactive {
  display: none !important;
  background-color: #d0d0ce !important;
  opacity: 0.24 !important;
  border-radius: none;
}
.uncertainBox .mat-mdc-slider .mdc-slider__track .mdc-slider__track--active {
  background-color: #d0d0ce;
  display: block !important;
  border-radius: 0px;
  height: 4px;
}
.uncertainBox .mdc-slider--disabled .mdc-slider__track .mdc-slider__track--active {
  display: none !important;
}
.uncertainBox .mdc-slider--disabled .mdc-slider__track {
  background-color: #a9abaa !important;
  height: 4px !important;
  border-radius: none;
}
.benignBox .mat-mdc-slider {
  width: 202px !important;
}
.benignBox .mdc-slider .mdc-slider__thumb-knob {
  background-color: #2166ac !important;
  border-radius: unset !important;
  width: 12px !important;
  height: 20px !important;
  padding: 2px 4px !important;
  border-style: none !important;
  border-width: calc(var(--mat-slider-handle-height, 20px) / 2) calc(var(--mat-slider-handle-width, 20px) / 2);
}
.benignBox .mat-mdc-slider .mdc-slider__track {
  height: 4px !important;
}
.benignBox .mdc-slider__thumb:last-child > .mdc-slider__thumb-knob {
  background-color: #2166ac !important;
}
.benignBox .mat-mdc-slider .mdc-slider__track--active_fill {
  border-color: #2166ac;
  background-color: #2166ac;
}
.benignBox .mat-mdc-slider .mdc-slider__track .mdc-slider__track--inactive {
  display: none !important;
  background-color: #d0d0ce !important;
  opacity: 0.24 !important;
  border-radius: none;
}
.benignBox .mat-mdc-slider .mdc-slider__track .mdc-slider__track--active {
  background-color: #d0d0ce;
  display: block !important;
  border-radius: 0px;
  height: 4px;
}
.benignBox .mdc-slider--disabled .mdc-slider__track .mdc-slider__track--active {
  display: none !important;
}
.benignBox .mdc-slider--disabled .mdc-slider__track {
  background-color: #2166ac !important;
  height: 4px !important;
  border-radius: none;
}
.pathogenicBox .mat-mdc-slider {
  width: 236px !important;
}
.pathogenicBox .mdc-slider .mdc-slider__thumb-knob {
  background-color: #b2182b !important;
  border-radius: unset !important;
  width: 12px !important;
  height: 20px !important;
  padding: 2px 4px !important;
  border-style: none !important;
  border-width: calc(var(--mat-slider-handle-height, 20px) / 2) calc(var(--mat-slider-handle-width, 20px) / 2);
}
.pathogenicBox .mat-mdc-slider .mdc-slider__track {
  height: 4px !important;
}
.pathogenicBox .mdc-slider__thumb:last-child > .mdc-slider__thumb-knob {
  background-color: #b2182b !important;
}
.pathogenicBox .mat-mdc-slider .mdc-slider__track--active_fill {
  border-color: #b2182b;
  background-color: #b2182b;
}
.pathogenicBox .mat-mdc-slider .mdc-slider__track .mdc-slider__track--inactive {
  display: none !important;
  background-color: #d0d0ce !important;
  opacity: 0.24 !important;
  border-radius: none;
}
.pathogenicBox .mat-mdc-slider .mdc-slider__track .mdc-slider__track--active {
  background-color: #d0d0ce;
  display: block !important;
  border-radius: 0px;
  height: 4px;
}
.pathogenicBox .mdc-slider--disabled .mdc-slider__track .mdc-slider__track--active {
  display: none !important;
}
.pathogenicBox .mdc-slider--disabled .mdc-slider__track {
  background-color: #b2182b !important;
  height: 4px !important;
  border-radius: none;
}
.mat-mdc-slider .mdc-slider__value-indicator {
  color: #373a36 !important;
}
.mdc-slider .mdc-slider__value-indicator-container {
  bottom: 33px !important;
}
.mat-mdc-slider .mdc-slider__value-indicator {
  background-color: unset !important;
}
.heatmap-tooltip-content,
.heatmap-pinned-tooltip-content {
  border: none !important;
  box-shadow: 0 4px 8px #0003, 0 6px 20px #00000030 !important;
}
.heatmap-pinned-tooltip-content {
  border: none !important;
  box-shadow: 0 4px 8px #0003, 0 6px 20px #00000030 !important;
}
.vf-button--secondary {
  border-width: medium !important;
}
.vf-button--secondary:hover {
  opacity: 1 !important;
  color: #3b6fb6 !important;
}
.vf-button--tertiary:hover {
  background: #707372 !important;
  border-color: #707372 !important;
  opacity: 1 !important;
}
.mdc-list {
  padding: 0 !important;
}
.mat-mdc-dialog-panel.entry-Dialog {
  max-width: 750px !important;
  width: 750px !important;
  height: 600px !important;
}
.mat-expansion-panel-spacing {
  margin: 0 !important;
}
.mat-expansion-panel-header-title {
  font-size: 19px;
  font-weight: 500;
  line-height: 28.5px;
}
.mat-expansion-panel-content {
  font-family: "IBM Plex Sans", sans-serif !important;
}
.mat-expansion-panel-header {
  font-family: "IBM Plex Sans", sans-serif !important;
  padding: 0 10px 0 24px !important;
  height: 36px !important;
}
.mat-expansion-panel-header.mat-expanded {
  background-color: #B9D4F1 !important;
}
.mat-expansion-panel-header.mat-expanded:hover {
  background: #D1E3F6 !important;
}
.mat-expansion-panel-header:not(.mat-expanded):hover {
  background: #D1E3F6 !important;
}
.mat-mdc-menu-panel {
  min-width: 160px !important;
  background-color: white !important;
}
.mat-mdc-radio-button .mdc-radio {
  padding: 3px !important;
}
.mat-mdc-tab-label-container {
  background: #f3f3f3;
}
.mat-mdc-tab.mdc-tab--active .mdc-tab__ripple::before,
.mat-mdc-tab.mdc-tab--active .mat-ripple-element,
.mat-mdc-tab-header-pagination .mat-ripple-element {
  background-color: transparent !important;
}
.mat-tab-header {
  margin-bottom: 16px;
}
.mat-mdc-text-field-wrapper {
  height: 10px;
}
.bond-Dialog {
  max-width: 80vw !important;
  width: 80vw;
  height: 90%;
}
.bond-Dialog .mat-dialog-container {
  padding: 0;
}
.ligand-total-Dialog {
  max-width: 50vw !important;
  width: 50vw;
  height: 50%;
}
.ligand-total-Dialog .mat-dialog-container {
  padding: 0;
}
.molstarDialog {
  max-width: 95vw !important;
  width: 95vw;
  height: 90%;
}
.molstarDialog .mat-dialog-container {
  padding: 0;
}
.mat-mdc-form-field-subscript-wrapper {
  display: none !important;
}
.mat-expansion-panel {
  box-shadow: none !important;
  border-bottom: 1px solid #e5e8ed;
}
.mat-expansion-panel-body {
  max-height: 275px;
  overflow-x: hidden !important;
  padding: 0 10px 16px 22px !important;
}
.mat-accordion .mat-expansion-panel:first-of-type {
  border-top-right-radius: unset !important;
  border-top-left-radius: unset !important;
  border-bottom-right-radius: unset !important;
  border-bottom-left-radius: unset !important;
}
.mat-accordion .mat-expansion-panel:last-of-type {
  border-top-right-radius: unset !important;
  border-top-left-radius: unset !important;
  border-bottom-right-radius: unset !important;
  border-bottom-left-radius: unset !important;
}
.mat-accordion .mat-expansion-panel {
  border-radius: unset !important;
}
.mat-bottom-sheet-container {
  padding: 0px 4px 0px 2px !important;
  background-color: white !important;
  z-index: 2 !important;
}
.mat-mdc-tab-label-container {
  border-style: none !important;
}
.mat-mdc-tab-group.mat-mdc-tab-group-stretch-tabs > .mat-mdc-tab-header .mat-mdc-tab:hover {
  border-bottom: 3px solid var(--neutral-600, #707372) !important;
  background: #fff !important;
}
.mat-mdc-tab.mdc-tab__content:hover {
  font-weight: bold;
}
.mdc-tab.mat-mdc-tab {
  border: 3px solid #f3f3f3;
  border-right: none;
  align-items: center;
  font-family: "IBM Plex Sans", sans-serif !important;
  padding: 14px 20px;
  position: relative;
}
.mdc-tab.mat-mdc-tab:hover {
  background-color: #fff !important;
  border-bottom: none !important;
}
.mdc-tab.mat-mdc-tab:focus .mat-ripple-element {
  background-color: transparent !important;
}
.mdc-tab.mat-mdc-tab .mdc-tab__text-label {
  color: var(--Neutral-900, #1a1c1a);
  text-align: center;
  letter-spacing: 0;
  font-size: 16px !important;
  font-style: normal;
  font-weight: 400;
  line-height: 27.2px;
}
.mdc-tab.mat-mdc-tab.mdc-tab--active .mdc-tab__text-label {
  font-weight: 700 !important;
}
.mdc-tab.mat-mdc-tab.mdc-tab--active {
  background: var(--Brand-50, #fff);
  border-bottom: none;
}
.mdc-tab.mat-mdc-tab::after {
  content: "";
  position: absolute;
  right: 0;
  top: 50%;
  width: 1px;
  height: 30px;
  background-color: #dedede;
  transform: translateY(-50%);
}
.mdc-tab.mat-mdc-tab .mdc-tab-indicator {
  height: 0;
  width: 0;
}
.vf-button-ghost {
  padding: 4px;
  display: flex;
  align-items: center;
  gap: 4px;
  color: #1a1c1a;
  font-size: 16px;
  font-weight: 400;
  line-height: 27.2px;
  cursor: pointer;
}
.vf-button-ghost:hover {
  background: #f3f3f3;
}
.mat-mdc-menu-item {
  min-height: 40px !important;
}
span.mat-mdc-menu-item {
  cursor: pointer;
}
.mat-mdc-menu-content .mat-mdc-menu-item:not([disabled]):hover {
  background-color: #D1E3F6;
}
span.mat-mdc-menu-item.small > .mat-mdc-menu-content,
.mat-mdc-menu-content .mat-mdc-menu-item .mat-mdc-menu-item-text {
  font-size: 16px !important;
  line-height: 27.2px !important;
}
.cdk-global-scrollblock {
  position: unset !important;
  overflow-y: unset !important;
}
.msp-plugin .msp-highlight-toast-wrapper {
  z-index: 1 !important;
}
.molstar-frozen .msp-viewport-controls-buttons,
.molstar-frozen .msp-viewport-controls-panel,
.molstar-frozen .msp-viewport-top-left-controls {
  display: none !important;
}
.msp-plugin .msp-sequence {
  background: #F3F3F3;
}
.msp-plugin .msp-sequence-select,
.msp-plugin .msp-sequence-select > select {
  background: #F3F3F3;
  display: None !important;
}
.msp-plugin .msp-sequence-wrapper-non-empty {
  top: 0 !important;
}
.msp-plugin .msp-sequence-present .msp-sequence-residue-focused {
  font-weight: bold !important;
}
.msp-plugin .msp-sequence-wrapper-non-empty {
  background: #F3F3F3;
}
.msp-plugin .msp-sequence-select > span {
  font-size: 14px !important;
  font-weight: 500 !important;
}
.msp-plugin .msp-sequence-wrapper .msp-sequence-present {
  font-size: 14px !important;
  font-weight: 500 !important;
}
.msp-plugin .msp-layout-standard-reactive .msp-layout-collapse-left .msp-layout-main {
  left: 0px !important;
}
.sequence-container .msp-sequence-wrapper-non-empty {
  z-index: 0;
  font-size: 85%;
}
.sequence-container .msp-sequence-chain-label {
  font-family:
    "IBM Plex Sans",
    Helvetica,
    Arial,
    sans-serif !important;
  font-size: 14px !important;
  font-weight: 500 !important;
  color: #000000 !important;
  border-bottom: solid 0.5px grey;
  padding-top: 4px;
  padding-bottom: 8px;
  position: absolute;
  z-index: 1;
  text-wrap: nowrap;
  overflow-x: hidden;
  line-height: 1.25;
  margin-top: 6px;
  margin-bottom: 0px;
  max-height: calc(4px + 8px + 1px + 1.25em);
  margin-inline: 10px;
  width: calc(100% - 2*10px);
  background-color: #f3f3f3;
}
.sequence-container .msp-sequence-chain-label:hover {
  text-wrap: initial;
  max-height: initial;
  background-color: #f3f3f3dd;
}
.sequence-container .msp-sequence-wrapper {
  margin-top: calc(6px + 4px + 8px + 1px + 1.25em/0.85);
  background-color: #f3f3f3;
}
gen-search-widget {
  display: block;
  width: 50% !important;
  margin: 0 auto;
}

/* node_modules/heatmap-component/build/heatmap-component.css */
/**
 * heatmap-component
 * @version 1.2.1
 * @link https://github.com/PDBeurope/heatmap-component
 * @license Apache-2.0
 */
:root {
  --tooltip-offset-x: 5px;
  --tooltip-offset-y: 8px;
}
.heatmap-main-div {
  font-family: sans-serif;
}
.heatmap-canvas-div {
  background-color: none;
}
.heatmap-svg[pointing-data] {
  cursor: pointer;
}
.heatmap-marker {
  stroke: black;
  stroke-width: 4;
  fill: none;
  pointer-events: none;
}
.heatmap-marker-x,
.heatmap-marker-y {
  stroke: black;
  stroke-width: 2;
  fill: none;
  pointer-events: none;
}
.heatmap-tooltip-box,
.heatmap-pinned-tooltip-box {
  z-index: 0;
  pointer-events: none;
}
.heatmap-tooltip-content,
.heatmap-pinned-tooltip-content {
  margin-left: var(--tooltip-offset-x);
  margin-bottom: var(--tooltip-offset-y);
  border: solid black 1px;
  padding-block: 0.35em;
  padding-inline: 0.7em;
  background-color: white;
  box-shadow: 0px 5px 15px rgba(0, 0, 0, 0.75);
  pointer-events: initial;
  width: max-content;
}
.heatmap-pinned-tooltip-close {
  position: absolute;
  top: -8px;
  right: -8px;
  width: 16px;
  height: 16px;
  border-radius: 1000px;
  background-color: black;
  border: solid black 1px;
  pointer-events: initial;
  cursor: pointer;
}
.heatmap-pinned-tooltip-close svg {
  position: absolute;
  width: 100%;
  height: 100%;
  fill: white;
  stroke: white;
}
.heatmap-pinned-tooltip-pin {
  position: absolute;
  left: 0px;
  bottom: 0px;
  width: calc(var(--tooltip-offset-x) / 0.6);
  height: calc(var(--tooltip-offset-y) / 0.6);
  z-index: -1;
}
.heatmap-pinned-tooltip-pin svg {
  fill: black;
}
.heatmap-overlay {
  position: absolute;
  width: 100%;
  height: 100%;
  pointer-events: none;
  display: flex;
  flex-direction: column;
  justify-content: center;
  align-items: center;
  z-index: 0;
}
.heatmap-overlay-shade {
  position: absolute;
  width: 100%;
  height: 100%;
  background-color: black;
  opacity: 0.4;
  z-index: -1;
}
.heatmap-overlay-message {
  margin: 5px;
  padding-block: 1em;
  padding-inline: 1.6em;
  text-align: center;
  font-size: 150%;
  font-weight: bold;
  background-color: white;
  border: solid black 1px;
  box-shadow: 0px 5px 15px rgba(0, 0, 0, 0.75);
}
.heatmap-brush-close {
  cursor: pointer;
}
.heatmap-brush-close .cross {
  fill: black;
  stroke: black;
}
.heatmap-brush-close .circle {
  fill: white;
  stroke: white;
}

/* angular:styles/global:styles */
/*# sourceMappingURL=styles.css.map */
